• 名称: MSTO-211H(人双向性肺癌细胞)
  • 货号: CBP60109
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CBP60109
I. General information 
Synonyms: MSTO-211H
Background: The MSTO-211H cell line was established in 1985 from the pleural effusion of a patient with biphasic mesothelioma of the lung.,Derived from metastatic site, lung
Species: Homo sapiens, human
Tissue: lung; derived from metastatic site: pleural effusion
Disease: biphasic mesothelioma
Gender: male,62 years, Caucasian
Morphology: fibroblast
Growth Mode: adherent
Doubling Time: 20 hrs
DNA Profile: Amelogenin: X,Y
CSF1PO: 11,12
D13S317: 11,14
D16S539: 13
D5S818: 12
D7S820: 8,12
THO1: 8,9.3
TPOX: 11
vWA: 16,18
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Oncogene: c-myc +; v-src +; v-abl +; v-erb B +; c-raf 1 +; H-ras +; K-ras +; N-ras +; N-myc -; L-myc -; c-myb -; c-fos -; v-fes -; v-fms -; v-sis -
Tumor Formation: Yes, tumors for med in approximately 20% of nude mice inoculated with MSTO-211H cells
Comments: The patient had not received prior radiation or chemotherapy. MSTO-211H cells have high affinity binding sites for EGF, and express Neuron specific enolase (NSE) and both the alpha and beta subunits of human chorionic gonadotropin (HCG).
L-DOPA decarboxylase (DDC), bombesin and neurotensin were not detected.The cells overexpress the c-myc protooncogene, and no gene rearrangement or amplification was observed.They are positive for the expression of v-src, v-abl, v-erb B, c-raf 1, Ha-ras, Ki-ras, and N-ras.Expression of N-myc, L-myc, c-myb, c-fos, v-fes, v-fms and v-sis oncogene expression was not detected.The cells can reach a saturation density of 400000 cells per sq cm, but will slough off of the surface as they attain this density.
For more information, please contact Cobioer (4008-750-250).

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