• 名称: JVM-2(人EB病毒感染的套细胞外周淋巴瘤细胞)
  • 货号: CBP60820
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CBP60820
I. General information 
Synonyms: JVM-2
Background: Leukemic cells from a patient with B-prolymphocytic leukemia were immortalized in vitro with Epstein-Barr virus (EBV) in the presence of phorbol-ester, TPA.
Species: Homo sapiens, human
Tissue: peripheral blood
Disease: Mantle Cell Lymphoma
Gender: female,63 years, Caucasian
Morphology: lymphoblast
Growth Mode: suspension
Doubling Time: about 48 hours
DNA Profile: Amelogenin: X
CSF1PO: 11
D13S317: 11,13
D16S539: 12,13
D5S818: 11,12
D7S820: 10,11
THO1: 6,9
TPOX: 8,11
vWA: 17
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: CD3-, CD5-, CD10-, CD19+, CD20+, CD23+ (verified at ATCC)
Oncogene: p53 [PubMed: 16434365]
Genes Expressed: p53 Ref,CD3-, CD5-, CD10-, CD19+, CD20+, CD23+ (verified at ATCC)
Comments: JVM-2 is characterized cytogenetically by t(11;14)(q13; q32) Ref Ref. JVM-2 cells retain p16 expression and exhibit low expression of cyclin D1. This cell line expresses cyclin D2 Ref. Based on the new classification of lymphomas, JVM-2 is considered a Mantle Cell Lymphoma (MCL) Ref Ref .
For more information, please contact Cobioer (4008-750-250).

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