• 名称: Human ADORA2B Ga15/CHO
  • 货号: CBP71019
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CBP71019
I. Background

The adenosine receptors ADORA2B is Gs and Gq/G11-coupled GPCR expressed in the large intestine, cecum, and urinary bladder. ADORA2B receptor mediates relaxation to adenosine in human small coronary arteries which is independent of NO but dependents in part on a K+-sensitive mechanism. Pharmacological or molecular biologic activation of ADORA2B receptor may prevent glomerular remodeling associated with glomerulosclerosis, renal disease, and abnormal growth associated with hypertension and diabetes.

 
II. Introduction
Host Cell:

CHO

Stability: 20 passages
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: Ham’s F12, 10% FBS, 400 μg/ml G418, 100 μg/ml Hygromycin B
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for ADORA2B receptor

 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

 

 

 

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