• 名称: NCI-H889(人小细胞肺癌细胞)
  • 货号: CBP60147
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CBP60147
I. General information 
Synonyms: NCI-H889
Background: This line was derived by A.F. Gazdar, H.K. Oie, J.D. Minna and associates from a lymph node metastasis taken from a patient prior to therapy.
Species: Homo sapiens, human
Tissue: lung; derived from metastatic site: lymph node
Disease: stage E, carcinoma; classic small cell lung cancer
Gender:  female,69 years, Caucasian
Morphology: epithelial
Growth Mode: clusters in suspension
DNA Profile: Amelogenin: X
CSF1PO: 10
D13S317: 11
D16S539: 8
D5S818: 12
D7S820: 8,9
THO1: 8,9.3
TPOX: 8,9
vWA: 17
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+20%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Comments: The cells express reduced levels of p53 mRNA compared to levels found in normal lung. There is a point mutation, a G to C transition (TGC to TCC), which results in a substitution of a serine for cysteine at codon 242.
The cells carry the K-ras 12 mutation.
For more information, please contact Cobioer (4008-750-250).

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