• 名称: SNU-1(人胃癌细胞)
  • 货号: CBP60501
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CBP60501
I. General information 
Synonyms: SNU-1
Background: SNU-1 was derived in 1984 by J. Park and associates from a poorly differentiated primary carcinoma of the stomach, taken prior to cytotoxic therapy.
Species: Homo sapiens, human
Tissue: stomach
Disease: gastric carcinoma
Gender: Asian,fmale, 44 years  adult
Morphology: epithelial
Growth Mode: suspension, multicell aggregates
Doubling Time: 26 hrs
DNA Profile: Amelogenin: X,Y
CSF1PO: 12,13
D13S317: 11,14
D16S539: 9,12
D5S818: 12,13
D7S820: 9,12
THO1: 8,9.3
TPOX: 8,10
vWA: 14
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: Blood Type O; Rh + ,The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG 72.
Receptor Expression: vasoactive intestinal peptide (VIP), expressed
Oncogene: myc +; erb B2 +
Tumor Formation: Yes, reported colony forming efficiency of 1.9% in semisolid medium. Ref
Comments: The cells are L-dopa decarboxylase (DDC) negative. SNU-1 cells were positive for VIP receptors but lacked gastrin receptors. No evidence of amplification or rearrangements was noted in the N-myc, L-myc, myb and EGF receptor genes. The cell line expressed levels of c-myc and c-erb-B-2 RNA that were comparable to other cell lines. There was no expression of the following genes: N-myc, L-myc, c-cis, IGF-2, or gastrin releasing peptide.
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