• 名称: SNU-16(人胃癌细胞)
  • 货号: CBP60502
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CBP60502
I. General information 
Synonyms: SNU-16
Background: SNU-16 was line derived in 1987 by J. Park and associates from ascites of a patient with poorly differentiated carcinoma of the stomach. The line was established from cells taken prior to chemotherapy. 
Species: Homo sapiens, human
Tissue: stomach; derived from metastatic site: ascites
Disease: gastric carcinoma
Gender: Asian,female, 33  years 
Morphology: epithelial
Growth Mode: suspension, multicell aggregates
Doubling Time: 27 hrs
DNA Profile: Amelogenin: X
CSF1PO: 12
D13S317: 8,12
D16S539: 11,13
D5S818: 10,13
D7S820: 12
THO1: 6,9
TPOX: 11
vWA: 16
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: Blood Type A; Rh + ,The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG 72.
Receptor Expression: vasoactive intestinal peptide (VIP), expressed , Ref
Oncogene: myc +; erb B2 +
Genes Expressed: myc +; erb B2 +,Blood Type A; Rh +,The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG 72.
Tumor Formation: Yes, the cells have a reported colony forming efficiency of 10% in semisolid medium.
Comments: SNU-16 cells were positive for VIP receptors but lacked gastrin receptors. The line was established from cells taken prior to chemotherapy.
No evidence of amplification or rearrangements was noted in the N-myc, L-myc, myb and EGF receptor genes. The c-myc proto-oncogene was apmplified, but expressed c-erb-B-2 RNA that were comparable to other cell lines. There was no expression of the following genes: N-myc, L-myc, c-cis, IGF-2, or gastrin releasing peptide.The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG-72. The cells are L-dopa decarboxylase (DDC) positive.
For more information, please contact Cobioer (4008-750-250).

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