• 名称: DMS114(人小细胞肺癌细胞)
  • 货号: CBP60171
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CBP60171
I. General information 
Synonyms: DMS114
Background: The line was established from cells from a mediastinal biopsy of a patient with small cell carcinoma of the lung. The patient had not received prior therapy.
Species: Homo sapiens, human
Tissue: lung
Disease: carcinoma; small cell lung cancer
Gender: male,68 years,Caucasian
Growth Mode: adherent
DNA Profile: Amelogenin: X
CSF1PO: 10,11
D13S317: 13
D16S539: 12
D5S818: 12
D7S820: 10,11
THO1: 8,9.3
TPOX: 8,11
vWA: 16,17
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: Leu 7 +; My23 +; CD11b +
Receptor Expression: epidermal growth factor (EGF); complement (CR3)
Genes Expressed: adrenocorticotropin (adrenocorticotropic hormone, ACTH); bombesin; glucagon; 17 beta estradiol; oxytocin - neurophysin (OT-NP)
Cellular Products: adrenocorticotropin (adrenocorticotropic hormone, ACTH); bombesin; glucagon; 17 beta estradiol; oxytocin - neurophysin (OT-NP)
Tumor Formation: Yes, Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 10(7) cells.
Comments: The patient had not received prior therapy.
The cells express HLA class I and class II antigens.
Early passages of the cells were contaminated with a bovine mycoplasma (Acholeplasma laidlawii) which was cured (prior to cryopreservation) with A. laidlawii antiserum and kanamycin.
For more information, please contact Cobioer (4008-750-250).

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