• 名称: Molt-4(人急性淋巴母细胞白血病细胞)
  • 货号: CBP60525
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CBP60525
I. General information 
Synonyms: Molt-4
Background: MOLT-4 was derived from the same patient as the MOLT-3 cell line (ATCC CRL-1552). The line was established from cells taken from a patient in relapse.
Species: Homo sapiens, human
Tissue: Blood
Disease: acute lymphoblastic leukemia
Gender: male,19 years 
Morphology: lymphoblast
Growth Mode: suspension
DNA Profile: Amelogenin: XY
CSF1PO: 11, 12, 13
D13S317: 12, 13
D16S539: 11, 14
D5S818: 12
D7S820: 8, 10, 11
THO1: 6, 8
TPOX: 8
vWA: 17, 18
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: CD1 (49%), CD2 (35%), CD3 A (26%) B (33%) C (34%), CD4 (55%), CD5 (72%), CD6 (22%), CD7 (77%)
Genes Expressed: high levels of terminal deoxynucleotidyl transferase (TdT) are produced.
Cellular Products: high levels of terminal deoxynucleotidyl transferase (TdT) are produced
Tumor Formation: Yes, in untreated nude mice, anti lymphocyte serum treated mice and X-irradiated mice,Ref
Comments: The patient had received prior multidrug chemotherapy. There is a G -> A mutation at codon 248 of the p53 gene.
P53 is not expressed.
The cells do not produce immunoglobulin or Epstein-Barr virus. The line was originally contaminated with mycoplasma but has been cured with antibiotics.
For more information, please contact Cobioer (4008-750-250).

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