• 名称: HCC1395(人乳腺癌细胞)
  • 货号: CBP60370
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CBP60370
I. General information 
Synonyms: HCC1395
Background: This cell line was initiated on 12/14/94 from a patient with a family history of cancer (patient's mother had breast cancer). The cell line took 14 months to establish.
Species: Homo sapiens, human
Tissue: mammary gland; breast/duct
Disease: TNM stage I, grade 3, primary ductal carcinoma
Gender: female,43 years adult, Caucasian, White
Morphology: epithelial
Growth Mode: adherent
DNA Profile: Amelogenin: X
CSF1PO: 11
D13S317: 9
D16S539: 11
D5S818: 11
D7S820: 10,12
THO1: 9.3
TPOX: 11
vWA: 15
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Receptor Expression: estrogen receptor, negative according to depositor
progesterone receptor, negative
Oncogene: her2/neu -, p53 +
Genes Expressed: Epithelial glycoprotein 2 (EGP2),cytokeratin 19
Cellular Products: Epithelial glycoprotein 2 (EGP2)
cytokeratin 19
Comments: The tumor was classified as TNM stage I, grade 3, invasive ductal carcinoma with 0 out of 34 lymph node metastasis.
The cells are poorly differentiated and vacuolated.
The cells are negative for expression of Her2-neu but positive for expression of p53.
HCC1395 is positive for the epithelial cell specific marker Epithelial Glycoprotein 2 (EGP2) and for cytokeratin 19.
The cells are negative for expression of estrogen receptors (ER -) according to depositor and negative for expression of progesterone receptors (PR -).
An EBV transformed lymphoblastoid cell line (HCC1395BL) from the same patient is available as ATCC CRL-2325.
For more information, please contact Cobioer (4008-750-250).

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