• 名称: HCC1419(人乳腺癌细胞)
  • 货号: CBP60371
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CBP60371
I. General information 
Synonyms: HCC1419
Background: This cell line was initiated on 12/28/94 from a patient who received prior chemotherapy with no previous family history of breast cancer. The line took 9 months to establish.
Species: Homo sapiens, human
Tissue: mammary gland; breast
Disease: TNM stage IIIA, grade 3,primary ductal carcinoma
Gender: female, 42 years, Hispanic
Morphology: epithelial
Growth Mode: adherent
DNA Profile: Amelogenin: X
CSF1PO: 10,12
D13S317: 9,12
D16S539: 11,12
D5S818: 10,12
D7S820: 11
THO1: 6,9.3
TPOX: 8
vWA: 16,17
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Receptor Expression: estrogen receptor, negative
progesterone receptor, negative
Oncogene: her2/neu +, p53 -
Genes Expressed: Epithelial glycoprotein 2 [EGP2]; cytokeratin 19
Cellular Products: Epithelial glycoprotein 2 [EGP2]; cytokeratin 19
Comments: The tumor was classified as TNM stage IIIA, grade 3, invasive ductal carcinoma with 5 out of 5 lymph node metastasis.
The cells are poorly differentiated.
The cells overexpress Her2-neu but are negative for expression of p53. HCC1419 is positive for the epithelial cell specific marker epithelial glycoprotein 2 (EGP2) and for cytokeratin 19.
The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR).
For more information, please contact Cobioer (4008-750-250).

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