• 名称: HCC70(人乳腺癌细胞)
  • 货号: CBP60375
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CBP60375
I. General information 
Synonyms: HCC70
Background: The HCC70 cell line was initiated from a primary ductal carcinoma on June 3, 1992, and took 44 months to establish.
Species: Homo sapiens, human
Tissue: breast; mammary gland/duct
Disease: TNM stage IIIA, grade 3, primary ductal carcinoma
Gender: female,49 years,Black
Morphology: epithelial
Growth Mode: adherent, The line grows as attached medium-sized epithelial cells.
DNA Profile: Amelogenin:X
CSF1PO:10,14
D13S317:12
D16S539:9,13
D5S818:12,13
D7S820:10,11
THO1:9
TPOX:10
vWA: 13,15
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Receptor Expression: progesterone receptor, not expressed
Oncogene: her2/neu -, p53 + (overexpressed)
Genes Expressed: Epithelial glycoprotein 2 [EGP2]; cytokeratin 19
Cellular Products: Epithelial glycoprotein 2 [EGP2]; cytokeratin 19
Comments: The cells are poorly differentiated.
The tumor was classified as TNM Stage IIIA, grade 3, invasive ductal carcinoma with metastases in 4 out of 17 lymph nodes.
The cells overexpress p53, and are negative for the expression of Her2-neu oncogenes.
HCC70 is positive for the epithelial cell specific marker Epithelial Glycoprotein 2 (EGP2) and for cytokeratin 19
The depositor of ATCC CRL-2315 initially reported the cells were positive for estrogen receptors. However, recent studies performed outside of ATCC have given conflicting results about the status of the estrogen receptor for these cells. An independent study at ATCC confirmed that ATCC CRL-2315, HCC70, is ER negative, PR negative and Her2 negative.
For more information, please contact Cobioer (4008-750-250).

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