• 名称: SK-BR-3(人乳腺腺癌细胞)
  • 货号: CBP60413
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CBP60413
I. General information 
Synonyms: SK-BR-3
Background: This cell line was derived by G. Trempe and L. J. Old in 1970 from pleural effusion cells of a patient, a White, Caucasian female, age 43, blood type A+, who had been treated with radiation, steroids, cytoxan and 5-fluorouracil.
Species: Homo sapiens, human
Tissue: mammary gland/breast; derived from metastatic site: pleural effusion
Disease: adenocarcinoma
Gender: female, Caucasian, 43 years
Morphology: epithelial
Growth Mode: adherent
Doubling Time: N/A
DNA Profile: Amelogenin: X
CSF1PO: 12
D13S317: 11,12
D16S539: 9
D5S818: 9,12
D7S820: 9,12
THO1: 8,9
TPOX: 8,11
vWA: 17
Cobioer’s Cell Line Authentication Service
Isoenzymes: AK-1, 1-2
ES-D, 1
G6PD, B
GLO-I, 2
PGM1, 1-2
PGM3, 1
Culture Medium: McCoy's 5a+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: Blood Type A; Rh+; HLA A11, Bw22(+/-), B40, B18
Receptor Expression: N/A
Oncogene: N/A
Genes Expressed: N/A
Cellular Products: N/A
Tumor Formation: Yes, in nude mice; forms poorly differentiated adenocarcinoma
Comments: The patient, a White, Caucasian female, age 43, blood type A+, had been treated with radiation, steroids, cytoxan and 5-fluorouracil.
No virus particles.
Ultrastructural features include microvilli and desmosomes, glycogen granules, large lysosomes, bundles of cytoplasmic fibrils.
The SK-BR-3 cell line overexpresses the HER2/c-erb-2 gene product.
For more information, please contact Cobioer (4008-750-250).

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