• 名称: DB(人B细胞淋巴瘤)
  • 货号: CBP60632
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CBP60632
I. General information 
Synonyms: DB
Background: The DB cell line was established by Walter J. Urba and Dan L. Longo from ascites fluid from a patient with a diffuse large cell lymphoma.
Species: Homo sapiens, human
Tissue: Ascites
Disease: large cell lymphoma
Gender: Caucasian,male,45 years
Morphology: lymphoblast
Growth Mode: suspension
DNA Profile: Amelogenin: X,Y
CSF1PO: 10,11
D13S317: 11,12
D16S539: 11
D5S818: 11
D7S820: 11
THO1: 6,8
TPOX: 8
vWA: 15,16
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: CD19 +; CD20 +; CD22 +; Hle-1 +; CD21 -; CD25 -
Cellular Products: immunoglobulin
Comments: The cells do not express HLA-DR, HLA-DQ, IgM , IgD or T cell rantigen receptor. Exposure of DB cells to phorbol esters (PMA or PdBu) that activate protein kinase C results in profound growth inhibition.
They are reported to be negative for the Epstein-Barr virus genome.The cells were cured of a prior mycoplasma contamination by a 21 day treatment with BM-cycline.
For more information, please contact Cobioer (4008-750-250).

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