• 名称: CFPAC-1(人胰腺导管腺癌细胞)
  • 货号: CBP60665
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CBP60665
I. General information 
Synonyms: CFPAC-1
Species: Homo sapiens, human
Tissue: pancreas; derived from metastatic: liver
Disease: ductal adenocarcinoma; cystic fibrosis
Gender: Caucasian,male,26 years
Morphology: epithelial
Growth Mode: adherent
Doubling Time: 32 hrs
DNA Profile: Amelogenin: X,Y
CSF1PO: 10
D13S317: 12
D16S539: 9,11
D5S818: 10,11
D7S820: 8,10
THO1: 8
TPOX: 8
vWA: 17
Cobioer’s Cell Line Authentication Service
Culture Medium: IMDM+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: Culture medium, 95%; DMSO, 5%
Tumor Formation: Yes, in nude mice,Yes, in the cheek pouch of cortisone treated hamsters
Comments: The cells exhibit ion transport activities consistent with cystic fibrosis and express the product of the CF gene (cystic fibrosis transmembrane regulator, CFTR).CFPAC-1 cells show no effect of cAMP agonists, adenyl cyclase stimulators or phosphodiesterase inhibitors on Cl- flux, but do respond to Ca++ ionophores with increase Cl- efflux.
The cells have the most common form of the CF mutation, deletion of three nucleotides resulting in the absence of phenylalanine at position 508.CFPAC-1 cells have epithelial morphology and polarization with apical microvilli, tight junctions and gap junctions.
For more information, please contact Cobioer (4008-750-250).

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