• 名称: Mino(人非霍奇金淋巴瘤细胞)
  • 货号: CBP60677
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CBP60677
I. General information 
Synonyms: Mino
Species: Homo sapiens, human
Tissue: peripheral blood/Mantle cell lymphoma (B cell non-Hodgkin's lymphoma)
Disease: Mantle Cell Lymphoma
Gender: Caucasian,male,64 years
Morphology: lymphoblast
Growth Mode: suspension
Doubling Time: about 72 hours
DNA Profile: Amelogenin: X,Y
CSF1PO: 9,11
D13S317: 12
D16S539: 11,12
D5S818: 11,12
D7S820: 10,11
THO1: 9.3
TPOX: 8,11
vWA: 14,17
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640  +15%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: CD3-, CD5+, CD10-, CD19+, CD20+, CD23- (verified at ATCC)
Oncogene: p53, p16 (INK4a), and p21(WAF1)
Genes Expressed: cyclin D2 and cyclin D3, p53, p16 (INK4a), and p21(WAF1)
Comments: The cells are large, growing singly and in small clumps in vitro. The immunophenotype by flow cytometry is compatible with MCL.
Western blots show expression of cyclin D1 but no detectable cyclin D2 and cyclin D3; the retinoblastoma protein is predominantly phosphorylated. There is expression of tumor suppressor gene products including p53, p16 (INK4a), and p21(WAF1).  Ref
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