• 名称: C-33 A(人子宫颈癌细胞)
  • 货号: CBP60707
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CBP60707
I. General information 
Synonyms: C-33 A
Species: Homo sapiens, human
Tissue: cervix
Disease: carcinoma
Gender: Caucasian,Female,66 years adult
Morphology: epithelial
Growth Mode: adherent
DNA Profile: Amelogenin: X
CSF1PO: 12
D13S317: 13
D16S539: 13,14
D5S818: 11,12
D7S820: 10
THO1: 7,8
TPOX: 9
vWA: 18,20
Cobioer’s Cell Line Authentication Service
Culture Medium: MEM + 10% FBS+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP)
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Oncogene: p53 +; pRB +
Genes Expressed: p53 +; pRB +
Tumor Formation: Yes, in nude mice; forms undifferentiated carcinoma
Comments: The line exhibited a hypodiploid karyotype initially, and an epithelial morphology.Karyological instability was observed with continued passage.
The retinoblastoma protein (pRB) is present but abnormal in size.Expression of p53 is elevated, and there is a point mutation at codon 273 resulting in a Arg -> Cys substitution. he cells are negative for human papillomavirus DNA and RNA.    The C-33 A cell line is one of a series of lines (see also ATCC CRL-1594 and ATCC CRL-1595) derived by N. Auersperg from cervical cancer biopsies.
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