• 名称: TOV-112D(人卵巢癌细胞)
  • 货号: CBP60694
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CBP60694
I. General information 
Synonyms: TOV-112D
Background: This cell line was initiated in October of 1992 from a patient with early onset ovarian cancer. The patient was of French-Canadian descent with an unknown family history of ovarian cancer.
Species: Homo sapiens, human
Tissue: Ovary
Disease: grade 3, stage IIIC, primary malignant adenocarcinoma; endometrioid carcinoma
Gender: Caucasian,female,42years adult
Morphology: epithelial
Growth Mode: adherent
DNA Profile: Amelogenin: X
CSF1PO: 12
D13S317: 8
D16S539: 9,12
D5S818: 10
D7S820: 9,10
THO1: 6
TPOX: 8,11
vWA: 18
Cobioer’s Cell Line Authentication Service
Culture Medium: 1:1 mixture of MCDB 105 medium and Medium 199,85%; FBS,15%
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Oncogene: her2/neu +, p53 (mutated, Arg --> His mutation at exon 6, codon 175) Ref
Genes Expressed: keratin
Cellular Products: keratin
Tumor Formation: The cells are tumorigenic in nude mice and form colonies in soft agar
Comments: Unlike TOV-21G (ATCC CRL-11730) and OV-90 (ATCC CRL-11732), the TOV-112D cell line does not exhibit a deletion at chromosome 3p24.
For more information, please contact Cobioer (4008-750-250).

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