• 名称: LOVO(人结肠癌肿瘤细胞)
  • 货号: CBP60032
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CBP60032
I. General information 
Synonyms: LOVO
Background: LoVo was initiated in 1971 from a fragment of a metastatic tumor nodule in the left supraclavicular region of a 56-year-old Caucasian male patient with a histologically proven diagnosis of adenocarcinoma of the colon.
Species: Homo sapiens, human
Tissue: colon; derived from metastatic site: left supraclavicular region
Disease: Dukes' type C, grade IV, colorectal adenocarcinoma
Gender: male,56 years
Morphology: epithelial
Growth Mode: adherent
DNA Profile: Amelogenin: XY
CSF1PO: 11,13,14
D13S317: 8, 11
D16S539: 9, 12
D5S818: 11, 12, 13
D7S820: 9.3,10, 11
THO1: 9.3
TPOX: 8,9
vWA: 17,18
Cobioer’s Cell Line Authentication Service
Culture Medium: DMEM+10%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: HLA A11, B15, B17, Cw1, Cw3; blood type B
Oncogene: myc +; myb + ; ras +; fos +; p53 +; sis -; abl -; ros -; src -
Genes Expressed: carcinoembryonic antigen (CEA) 908 ng/10 6 cells/10 days.  The cells are negative for expression of CSAp (CSAp-) and colon antigen 3. 
Cellular Products: carcinoembryonic antigen (CEA) 908 ng/10 exp6 cells/10 days
Tumor Formation: Yes, in nude mice,(Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 10(7) cells)
Comments: The cells are negative for expression of CSAp (CSAp-) and colon antigen 3.The line is positive for expression of c-myc, K-ras, H-ras, N-ras, Myb, sis and fos oncogenes.
N-myc and sis oncogene expression were not detected.
Tumor specific nuclear matrix proteins CC-3 and CC-4 are expressed.
For more information, please contact Cobioer (4008-750-250).

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