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NCI-H727(人肺支气管良性肿瘤)

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NCI-H727(人肺支气管良性肿瘤)

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产品编号
CBP60182
货号:
CBP60182
品牌:
Cobioer
规格:
T-25 Flask
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CBP60182
I. General information 
Synonyms: NCI-H727
Background: This line was derived by A.F. Gazdar, H.K. Oie, J.D. Minna and associates from tissue taken prior to therapy.
Species: Homo sapiens, human
Tissue: lung, bronchus
Disease: carcinoid
Gender: female,65 years,Caucasian
Morphology: epithelial
Growth Mode: adherent
DNA Profile: Amelogenin: X
CSF1PO: 11,12
D13S317: 11
D16S539: 11,13
D5S818: 11,12
D7S820: 8,10
THO1: 8
TPOX: 8
vWA: 14,15
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+20%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Receptor Expression: epidermal growth factor (EGF)
Genes Expressed: neuromedin B (NMB)
Cellular Products: neuromedin B (NMB)
Comments: This is the best differentiated of the available bronchial carcinoid lines.The cells express easily detectable levels of p53 mRNA compared to levels found in normal lung.The cells are able to synthesize the peptide NMB (at 0.1 pmol/mg protein), but not the gastrin releasing peptide (GRP).
The cell line secretes a parathyroid hormone-like protein which is calcium stimulated through a protein kinase C pathway.Growth of NCI-H727 cells is inhibited by epidermal growth factor (EGF) receptor monoclonal antibodies.
For more information, please contact Cobioer (4008-750-250).
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