|I. General information|
|Background:||SNU-387 was derived in 1990 by J.-G. Park and associates from a primary hepatocellular carcinoma taken from a Korean patient who had been treated by transcatheter arterial embolization with lipoidol plus a combination of doxorubicin and mitomycin-C.
Tumor cells were initially cultured in ACL-4 medium supplemented with 5% heat-inactivated fetal bovine serum. After establishment, cultures were maintained in RPMI 1640 supplemented with 10% heat inactivated fetal bovine serum.
|Species:||Homo sapiens, human|
|Disease:||grade IV/V, pleomorphic hepatocellular carcinoma|
|Gender:||female，41 years， Asian|
|Doubling Time:||61 hrs|
|DNA Profile:||Amelogenin: X
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|Antigen Expression:||Blood Type O; Rh +|
|Comments:||Grossly, the original tumor was single nodular.
Histologically, it was predominantly compact and minor trabecular type.
The cultured cells contain a single nucleus.
Hepatitis B virus (HBV) DNA was detected by Southern blot hybridization.
HBV genomic RNA was not expressed.
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