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OVCAR3(人卵巢腺癌细胞)

科研细胞

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药靶细胞

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OVCAR3(人卵巢腺癌细胞)

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产品编号
CBP60294
货号:
CBP60294
品牌:
Cobioer
规格:
T-25 Flask
物种:
组织:
卵巢
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CBP60294
I. General information 
Synonyms: OVCAR3
Background: The NIH:OVCAR-3 line was established in 1982 by T.C. Hamilton, et al. from the malignant ascites of a patient with progressive adenocarcinoma of the ovary.
Species: Homo sapiens, human
Tissue: ovary
Disease: adenocarcinoma
Gender: female, 60 years, Caucasian
Morphology: epithelial
Growth Mode: adherent
DNA Profile: Amelogenin: X
CSF1PO: 11,12
D13S317: 12
D16S539: 12
D5S818: 11,12
D7S820: 10
THO1: 9,9.3
TPOX: 8
vWA: 17
Cobioer’s Cell Line Authentication Service
Culture Medium: RPMI-1640+20%FBS
We strongly suggest to purchase the complete medium from Cobioer.
Cryopreservation medium: 90%FBS+10%DMSO
Receptor Expression: Androgen receptor, positive; estrogen receptor, positive; progesterone receptor, positive
Tumor Formation: Yes, Forms colonies in soft agar
Yes, in nude mice inoculated subcutaneously with 10(7) cells
(Tumors developed within 21 days at 100% frequency (5/5).)
Comments: Forms colonies in soft agar and has an abnormal karyotype.
Resistant to clinically relevant concentrations of adriamycin, melphalan and cisplatin.
Both cultured cells and xenografts exhibit androgen and estrogen receptors.
Xenograft models have been used to show that treatment with 17 beta estradiol can induce progesterone receptors in this human ovarian carcinoma.
For more information, please contact Cobioer (4008-750-250).
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