|I. General information|
|Background:||It was originated by A.J. Hackett, et al. along with the Hs 578Bst (see ATCC HTB-125), which is a normal fibroblast-like line from the same patient.
The Hs 578T cell strain was derived from a carcinoma of the breast.
|Species:||Homo sapiens, human|
|Gender:||female， 74 years adult，Caucasian|
|DNA Profile:||Amelogenin: X
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|Culture Medium:||DMEM+10%FBS+0.01 mg/ml insulin
We strongly suggest to purchase the complete medium from Cobioer.
|Receptor Expression:||Receptor expression: estrogen receptor, not expressed Ref|
|Tumor Formation:||No, in immunosuppressed mice
Yes, in semisolid medium
|Comments:||The Hs 578T line had a mixed polygonal morphology initially, but a stellate cell type was selected for during passage and by cloning.
Aggregates of casein protein granules, desmosomes, tight junctions, lipid droplets and vesicularized smooth endoplasmic reticulum were observed by electron microscopy.
As with Hs 578Bst, no estrogen receptors or endogenous viruses were detected.
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