|I. General information|
|Background:||The cell line Ri-1 has been established from the peripheral blood of a 48-year-old female patient with B-cell lymphoma. This EBV-negative cell line with 14q+ abnormality was shown to be at an intermediate stage of B-cell differentiation. Ri-1 expresses surface and cytoplasmic immunoglobulin (IgM kappa), HLA-DR, CD20, CD38 and FMC7. Rearranged heavy-light chain genes and one rearranged kappa light-chain gene was detected as well as a kappa and lambda light-chain gene in germ-line configuration.|
|Species:||human (Homo sapiens)|
|Disease:||Human Caucasian B-cell lymphoma|
|DNA Profile:||Cobioer’s Cell Line Authentication Service|
We strongly suggest to purchase the complete medium from Cobioer.
|Subculture Routine:||Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37°C. Cell growth is very slow after resuscitation; large amounts of debris present.|
|Comments:||For more information, please contact Cobioer (4008-750-250).|