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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
ME180(人子宫颈鳞状癌细胞)
CBP60645 | |
I. General information | |
Synonyms: | ME180 |
Background: | This line was derived from a highly invasive squamous cell carcinoma with irregular cell clusters and no significant keratinization. |
Species: | Homo sapiens, human |
Tissue: | cervix; derived from metastatic site: omentum |
Disease: | epidermoid carcinoma |
Gender: | Caucasian,female,66 years |
Morphology: | epithelial |
Growth Mode: | adherent |
DNA Profile: | Amelogenin: X CSF1PO: 11 D13S317: 11,13 D16S539: 12,13 D5S818: 12 D7S820: 9,10 THO1: 8,9.3 TPOX: 8,10 vWA: 15,17 Cobioer’s Cell Line Authentication Service |
Culture Medium: |
McCoy's 5a+10%FBS ME180完全培养基,# CBP60645M |
Cryopreservation medium: | 90%FBS+10%DMSO |
Antigen Expression: | Blood Type A; Rh+; HLA A1, A11, B5(+/-), B40 |
Oncogene: | p53 +; pRB + |
Genes Expressed: | N/A |
Tumor Formation: | Yes, in nude mice; forms well differentiated epidermoid carcinoma (grade I) |
Comments: | Desmosomal attachments were observed between cells in monolayer culture and cytoplasmic tonofilaments were noted. Contamination with Mycoplasma arginini was detected and eliminated in 1970. Growth of ME-180 cells is inhibited by tumor necrosis factor alpha (TNF alpha).The cells contain human papillomavirus (HPV) DNA with greater homology to HPV-68 than HPV-18. For more information, please contact Cobioer (4008-750-250). |
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