This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1 (CCL2), a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
|Stability:||20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Freeze Medium:||90% FBS+10% DMSO|
|Culture Medium:||F12K+10% FBS+2 μg/ml puromycin+ 100 μg/ml Hygromycin B|
|Storage:||Liquid nitrogen immediately upon delivery|
Functional assay for CCR2 receptor
|Ⅲ. Description of Host Cell Line|
|Ⅳ. Representative Data|