This gene encodes the D2 subtype of the dopamine receptor, which is coupled to Gi subtype of G protein-coupled receptor. This G protein-coupled receptor inhibits adenylyl cyclase activity. In mice, regulation of D2R surface expression by the neuronal calcium sensor-1 (NCS-1) in the dentate gyrus is involved in exploration, synaptic plasticity and memory formation.A recent study has shown a potential role for D2R in retrieval of fear memories in the prelimbic cortex.
|Stability:||20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Freeze Medium:||90% FBS+10% DMSO|
|Culture Medium:||DMEM+10%FBS+400ug/ml G418|
|Storage:||Liquid nitrogen immediately upon delivery|
Functional assays for DRD2 receptor
|Ⅲ. Description of Host Cell Line|
|Ⅳ. Representative Data|