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科研细胞
药靶细胞
标准品
MC4R/Luc/HEK293
| CBP71318 | |
| I. Background | |
|
The melanocortin family consists of five melanocortin G-Protein-coupled receptors (designated MC1-5R). The melanocortins, α-, β- and γ-melanocyte-stimulating hormones (MSHs), are peptides derived from a precursor protein POMC, and play important roles in energy balance, reproductive function, pigmentation and inflammation. MC4 receptors with high affinities for α-MSH and ACTH are expressed almost exclusively in the CNS and appear to play a prominent role in energy homeostasis. |
|
| II. Introduction | |
| Host Cell: |
HEK293 |
| Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+400ug/ml G418 |
| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): |
Functional assay for MC4 receptor |
| Transducer: | Gs |
| Ⅲ. Description of Host Cell Line | |
| Organism: | Human |
| Tissue: | kidney |
| Morphology: | Epithelial |
| Growth Properties: | Adherent |
| Ⅳ. Representative Data | |
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