NPY4R (Neuropeptide Y Receptor Y4) is a Protein Coding gene. Diseases associated with NPY4R include Alzheimer Disease and Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and peptide YY receptor activity.
|Expressed gene:||GenBank accession number NM_000647.3; no expressed tags|
|Stability:||20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)|
C-C chemokine receptor type 2, CCR2
|Freeze Medium:||90% FBS+10% DMSO|
|Culture Medium:||F12K+10%FBS+400ug/ml G418|
|Storage:||Liquid nitrogen immediately upon delivery|
Functional assay for NPY4R receptor
|Ⅲ. Description of Host Cell Line|
Concentration-dependent stimulation of intracellular calcium mobilization by MCP-1 in CCR2/Ga16/HEK293 and HEK293 cells.
Figure 1. MCP-1-induced concentration-dependent stimulation of intracellular calcium mobilization in CCR2/Ga16/HEK293 and HEK293 cells. The cells were loaded with Calcium-4 prior to stimulation with an CCR2 receptor agonist, MCP-1. The intracellular calcium change was measured by FlexStation.