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Package-Ref™ Lung Cancer Reference Standard Package

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Package-Ref™ Lung Cancer Reference Standard Package

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产品编号
CBP90022
货号:
CBP90022
品牌:
Cobioer
规格:
1ug/vial * 6 vials
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Package-Ref™ Lung Cancer Reference Standard Package
Cat No. CBP90022
Format Genomic DNA
Description 包含6管标准品,作为参考品、质控品、精密度、检测限
             
Panel-Ref™ gDNA Cocktail III Reference Standard
Gene AA Change CDS Change Exon Cosmic ID Expected AF Chr position (GRCh37)
EFGR p.E746_A750delELREA c.2235_2249del15 GGAATTAAGAGAAGC>- 19 COSM6223 5% chr7:55242465_55242479
EFGR p.L858R c.2573T>G 21 COSM6224 5% chr7:55259515
EGFR p.T790M c.2369C>T 20 COSM6240 5% chr7:55249071
EGFR p.G719S c.2155G>A 18 COSM6252 5% chr7:55241707
BRAF p.V600E c.1799T>A 15 COSM476 内源突变 chr7:140453136
KRAS p.G12D c.35G>A 2 COSM521 5% chr12:25398284
KRAS p.Q61H c.183A>C 3 COSM554 内源突变 chr12:25380275
PIK3CA p.E545K c.1633G>A 10 COSM763 5% chr3:178936091
PIK3CA p.H1047R c.3140A>G 20 COSM775 内源突变 chr3:178952085
EML4-ALK E13-A20 DNA Translocation N/A COSF408 5% N/A
CCDC6-RET E1-E12 DNA Translocation N/A COSF1271 5% N/A
ERBB2 CNV Amplication N/A N/A CN=6 N/A
MYC CNV Amplication N/A N/A CN=10 N/A
             
Panel-Ref™ gDNA Cocktail IV Reference Standard
Gene AA Change CDS Change Exon Cosmic ID Expected AF Chr position (GRCh37)
EGFR p.G719S c.2155G>A 18 COSM6252 5% chr7:55241707
BRAF p.V600K c.1798_1799GT>AA 15 COSV56057713 5% chr7:140453136_140453137
PIK3CA p.H1047R c.3140A>G 20 COSM775 5% chr3:178952085
KRAS p.G13D c.38G>A 2 COSM532 5% chr12:25398281
NRAS p.G12D c.182A>G 3 COSM584 5% chr1:115258747
BRCA2 p.I2675Dfs*6 c.8021dup 18 COSM2071519 5% chr13:32937360
SLC34A2-ROS1 E4-E32 DNA Translocation N/A COSF1197 5% N/A
EML4-ALK E6-A20 DNA Translocation N/A COSF408 5% N/A
CCDC6-RET E1-E12 DNA Translocation N/A COSF1271 5% N/A
MET Exon 14 Skippig c.3082+1G>T N/A COSM6108462 5% chr7:116412044
ERBB2 CNV Amplication N/A N/A CN=6 N/A
MYC CNV Amplication N/A N/A CN=7 N/A
             
Panel-Ref ™ gDNA Cocktail V Reference Standard
Gene AA Change CDS Change Exon Cosmic ID Expected AF Chr position (GRCh37)
EFGR p.E746_A750delELREA c.2235_2249del15 GGAATTAAGAGAAGC>- 19 COSM6223 3% chr7:55242465_55242479
EFGR p.L858R c.2573T>G 21 COSM6224 3% chr7:55259515
EGFR p.T790M c.2369C>T 20 COSM6240 3% chr7:55249071
EGFR p.G719S c.2155G>A 18 COSM6252 3% chr7:55241707
BRAF p.V600E c.1799T>A 15 COSM476 内源突变 chr7:140453136
KRAS p.G12D c.35G>A 2 COSM521 3% chr12:25398284
KRAS p.Q61H c.183A>C 3 COSM554 内源突变 chr12:25380275
PIK3CA p.E545K c.1633G>A 10 COSM763 3% chr3:178936091
PIK3CA p.H1047R c.3140A>G 20 COSM775 内源突变 chr3:178952085
EML4-ALK E13-A20 DNA Translocation N/A COSF408 3% N/A
CCDC6-RET E1-E12 DNA Translocation N/A COSF1271 3% N/A
ERBB2 CNV Amplication N/A N/A CN=4 N/A
             
Panel-Ref™ gDNA Cocktail VI Reference Standard
Gene AA Change CDS Change Exon Cosmic ID Expected AF Chr position (GRCh37)
BRAF p.V600E c.1799T>A 15 COSM476 5% chr7:140453136
PIK3CA p.H1047R c.3140A>G 20 COSM775 5% chr3:178952085
KRAS p.G13D c.38G>A 2 COSM532 5% chr12:25398281
BRCA2 p.I2675Dfs*6 c.8021dup 18 COSM2071519 5% chr13:32937360
             
Panel-Ref™ gDNA Cocktail Ⅶ Reference Standard
Gene AA Change CDS Change Exon Cosmic ID Expected AF Chr position (GRCh37)
EGFR p.E746_A750del c.2236_2250del15 19 COSM6225 5% chr7:55242466_55242480
EGFR p.S768I c.2303G>T 20 COSM6241 5% chr7:55249005
EGFR p.L861Q c.2582T>A 21 COSM6213 5% chr7:55259524
MET CNV Amplification N/A N/A CN=6 N/A
ERBB2 p.A775_G776insYVMA c.2324_2325ins12 20 COSM12558 5% chr17:37880996_37880997
KRAS p.G12V c.35G>T 2 COSM520 5% chr12:25398284
PIK3CA p.E542K c.1624G>A 10 COSM760 5% chr3:178936082
KRAS p.Q61H c.183A>C 3 COSM554 5% chr12:25380275
BRAF p.V600E c.1799T>A 15 COSM476 内源突变 chr7:140453136
PIK3CA p.H1047R c.3140A>G 20 COSM775 内源突变 chr3:178952085
EGFR p.G719C c.2155G>T 18 COSM6253 5% chr7:55241707
CD74-ROS1 E6-E34 DNA Translocation N/A COSF1200 5% N/A
NRAS p.Q61K c.181C>A 3 COSM580 5% chr1:115256530
IDH1 p.R132C c.394C>T 4 COSM28747 5% chr2:209113113
             
阴性对照
Mutation 0%
Fusion 0%
Expected %AF CN=2
             
Product Information 
Intended Use Research Use Only
Unit Size 1ug/vial * 6 vials
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Storage 4°C
Expiry 36 months from the date of manufacture
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