|GITRL (CD357; AITRL; TNLG2A), a part of the tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), is mainly expressed on antigen presenting cells. GITRL engages with the GITR receptor as a co-stimulatory signal to promote lymphocyte activation.|
Recombinant CHO cell constitutively expressing full length human GITRL. Surface expression is confirmed by flow cytometry.
|Stability:||32 passages(in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Freeze Medium:||90% FBS+10% DMSO|
F12K +10%FBS +400ug/ml hygromycin
|Application(s):||This cell line is useful for stimulating human GITR on immune cells, as well as binding assays for GITR.|
|IV. Description of Host Cell Line|
|Disease:||Hamster Chinese ovary|
|Ⅴ. Representative Data|
Figure 1. Recombinant CHO cell constitutively expressing full length human GITRL. Surface expression is confirmed by flow cytometry.