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mouse FCGR2B/TCR activator/CHO

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mouse FCGR2B/TCR activator/CHO

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产品编号
CBP74101
货号:
CBP74101
品牌:
Cobioer
规格:
T-25 Flask
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CBP74101
I. Background
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
 
II. Description

FCGR2B (FcγRIIb) is a Protein Coding gene. Diseases associated with FCGR2B include Systemic Lupus Erythematosus and Malaria. Among its related pathways are Microglia Activation During Neuroinflammation: Overview and Osteoclast differentiation. Gene Ontology (GO) annotations related to this gene include IgG binding. 

 
III. Introduction
Host Cell: CHO
Expressed gene: FCGR2B(FcγRIIb)
Stability: 32 passages(in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s): Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, Fc fragment of IgG receptor IIb
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+500ug/ml hygromycin
Mycoplasma Testing: Negative
Storage: Liquid nitrogen
 
IV. Description of Host Cell Line
Organism: Mouse
Tissue: Ovary
Disease: Hamster Chinese ovary
Morphology: Epitheloid cell
Growth Properties: Adherent
 
Ⅴ. Representative Data

Figure 1.Recombinant CHO cells constitutively expressing FCGR2B(FcγRIIb).

 
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  • Manual download:mouse FCGR2BTCR activatorCHO CBP74101.pdf

    大小:
    2022-04-06
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