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OX40/HEK293

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CBP74049

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CBP74049

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Cobioer

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T-25 Flask

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CBP74049
I. Background
OX40 (CD134) is a co-stimulatory receptor expressed on the surface of CD4+ and CD8+ T cells 24 to 48 hours after activation. Binding of OX40 to its ligand, OX40L (CD252), present on dendritic cells, potentiates T cell survival and increases cytokine production. OX40 has been shown to activate NF-κB-mediated memory cell generation through its interaction with adaptor proteins TRAF2 and TRAF5. OX40 has a critical role in the maintenance of an immune response beyond the first few days and onwards to a memory response.

II. Description
Recombinant HEK293 stably expressing human OX40 (TNF receptor superfamily member 4, TNFRSF4, ACT35; CD134; IMD16; TXGP1L, GenBank Accession #NM_003327).

III. Introduction
Host Cell:	HEK293
Expressed gene:	OX40
Stability:	32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):	TNFRSF4, ACT35, IMD16, TXGP1L, Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, CD134
Freeze Medium:	90% FBS+10% DMSO
Culture Medium:	DMEM+10%FBS+1ug/ml puromycin
Mycoplasma Testing:	Negative
Storage:	Liquid nitrogen
Application(s):	Binding Assay,FACS
IV. Description of Host Cell Line
Organism:	Homo sapiens,human
Tissue:	Embryonic kidney
Disease:	Normal
Morphology:	Epitheloid cell
Growth Properties:	Adherent

Ⅴ. Representative Data

Figure 1.Recombinant HEK293 stably expressing human OX40 (TNF receptor superfamily member 4, TNFRSF4, ACT35; CD134; IMD16; TXGP1L, GenBank Accession #NM_003327).