TLR3 (Toll Like Receptor 3) is a Protein Coding gene. Diseases associated with TLR3 include Encephalopathy, Acute, Infection-Induced 2 and Human Immunodeficiency Virus Type 1. Among its related pathways are Activated TLR4 signalling and Toll-like Receptor Signaling Pathway. Gene Ontology (GO) annotations related to this gene include identical protein binding and transmembrane signaling receptor activity.
|Stability:||32 passages(in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Synonym(s):||TLR3/NF-kB cell line；|
|Freeze Medium:||90% FBS+10% DMSO|
MEM + 10% Foetal Bovine Serum (FBS)+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) +1ug/ml puromycin+100ug/ml hygromycin
Screen for activators or inhibitors of TLR3 signaling in a cellular context
|III. Description of Host Cell Line|
|IV. Representative Data|
Figure 1. Detect Luciferase assay by Promega Bright-Glo Luciferase Assay System. TLR3/NF-kB Reporter-HEK293 cells were stimulated by Poly(I:C), the S/B was 57-fold.