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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
TP53 p.H193R Reference Standard
CBP10147
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Format | Genomic DNA |
Description | TP53 H193R lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). H193R has not been biochemically characterized in human cells, but results in decreased Tp53 transactivation ability in yeast assays and is predicted to result in decreased Tp53 stability and protein expression by computational modeling (PMID: 9627118, PMID: 21763698). |
Technical Data | |
DNA Change: | c.578A>G |
AA Change | p.H193R |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305 |
Cosmic ID | COSM10742 |
Chr position(GRCh37) | chr17:7578271 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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