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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CLEC2D aAPC Cell
CBP74138 | |
I. Background | |
CLEC2D (C-type lectin domain family 2 member D) is also known as CLAX, LLT1, OCIL is receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis, inhibits osteoclast formation, inhibits bone resorption and modulates the release of interferon-gamma. It is also a ligand for the human NKR-P1A (CD161) receptor, present on NK cells and T cells. Furthermore, The reference shows the pathway may as a potential immunotherapy targets. | |
II. Introduction | |
Expressed gene: |
CLEC2D |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: |
F12K+10%FBS+600ug/ml hygromycin+2ug/ml puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
III. Representative Data | |
Figure 1. Dose Response of CD161 Blocking Antibody in CD161 Effector Reporter Cells (Clone 8) With CLEC2D aAPC Cells. |
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