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科研细胞
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HCC202（人乳腺原发性导管癌）
| CBP60416 | |
| I. General information | |
| Synonyms: | HCC202 |
| Background: | The HCC202 cell line was initiated from a primary ductal carcinoma on September 5, 1992, and took 41 months to establish. |
| Species: | Homo sapiens, human |
| Tissue: | breast; mammary gland/duct |
| Disease: | TNM stage IIIA, grade 3, primary ductal carcinoma |
| Gender: | female， Caucasian, White， 82 years |
| Morphology: | epithelial |
| Growth Mode: | adherent, The line grows as attached medium-sized epithelial cells with some floating cells |
| Doubling Time: | N/A |
| DNA Profile: | Amelogenin: X CSF1PO: 10 D13S317: 8,9 D16S539: 13 D5S818: 11,13 D7S820: 8,12 THO1: 6 TPOX: 8,9 vWA: 16 Cobioer’s Cell Line Authentication Service |
| Culture Medium: | RPMI-1640+20%FBS We strongly suggest to purchase the complete medium from Cobioer. |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | N/A |
| Receptor Expression: | estrogen receptor, negative progesterone receptor, negative |
| Oncogene: | her2/neu +, p53 - |
| Genes Expressed: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Cellular Products: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Tumor Formation: | N/A |
| Comments: | The tumor was classified as TNM Stage IIIA, grade 3, invasive ductal carcinoma with metastases in 4 out of 19 lymph nodes. The cells are poorly differentiated. The cells are positive for expression of Her2-neu, but are negative for expression of p53. HCC202 is positive for the epithelial cell specific marker Epithelial Glycoprotein 2 (EGP2) and for cytokeratin 19. The cells are negative for expression of estrogen receptor (ER -) and progesterone receptor (PR -). For more information, please contact Cobioer (4008-750-250). |
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