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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CFPAC-1(人胰腺导管腺癌细胞)
CBP60665 | |
I. General information | |
Synonyms: | CFPAC-1 |
Species: | Homo sapiens, human |
Tissue: | pancreas; derived from metastatic: liver |
Disease: | ductal adenocarcinoma; cystic fibrosis |
Gender: | Caucasian,male,26 years |
Morphology: | epithelial |
Growth Mode: | adherent |
Doubling Time: | 32 hrs |
DNA Profile: | Amelogenin: X,Y CSF1PO: 10 D13S317: 12 D16S539: 9,11 D5S818: 10,11 D7S820: 8,10 THO1: 8 TPOX: 8 vWA: 17 Cobioer’s Cell Line Authentication Service |
Culture Medium: | IMDM+10%FBS We strongly suggest to purchase the complete medium from Cobioer. |
Cryopreservation medium: | 90%FBS+10%DMSO |
Antigen Expression: | Culture medium, 95%; DMSO, 5% |
Tumor Formation: | Yes, in nude mice,Yes, in the cheek pouch of cortisone treated hamsters |
Comments: | The cells exhibit ion transport activities consistent with cystic fibrosis and express the product of the CF gene (cystic fibrosis transmembrane regulator, CFTR).CFPAC-1 cells show no effect of cAMP agonists, adenyl cyclase stimulators or phosphodiesterase inhibitors on Cl- flux, but do respond to Ca++ ionophores with increase Cl- efflux. The cells have the most common form of the CF mutation, deletion of three nucleotides resulting in the absence of phenylalanine at position 508.CFPAC-1 cells have epithelial morphology and polarization with apical microvilli, tight junctions and gap junctions. For more information, please contact Cobioer (4008-750-250). |

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