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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
c-Kit Y823D/BaF3
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CBP73208 |
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| I. Introduction | |
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Cell Line Name： |
c-Kit Y823D/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| II.Background | |
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KIT Y823D lies within the protein kinase domain of the Kit protein (UniProt.org). Y823D confers a gain of function on Kit, as indicated by constitutive phosphorylation of Kit in cultured cells (PMID: 14695343, PMID: 20633291). |
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| III. Representative Data | |
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1.WB of c-Kit Y823D/BaF3
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2.Sanger of c-Kit Y823D/BaF3
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3. Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 c-KIT Y823D (C1). |
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