南京科佰生物科技有限公司官方网站欢迎您的光临！
免费咨询热线： 4008-750-250
科研细胞
药靶细胞
标准品
NGS靶向捕获探针
EGFR H773_V774insAH/BaF3
| CBP73220 | |
| I. Introduction | |
|
Cell Line Name： |
EGFR H773_V774insAH/BaF3 |
|
Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
|
Application: |
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
|
Freeze Medium: |
90% FBS+10% DMSO
|
|
Complete Culture Medium: |
RPMI-1640+10%FBS
|
|
Mycoplasma Status: |
Negative |
| II.Background | |
|
EGFR H773_V774insAH results in the insertion of two amino acids within the drug-binding pocket in the protein kinase domain of the Egfr protein between amino acids 773 and 774 (UniProt.org, PMID: 23371856). H773_V774insAH has not been biochemically characterized, but is predicted to result in a gain of function based on the effect of other Egfr exon 20 insertion mutations (PMID: 24353160). |
|
| III. Representative Data | |
|
1. WB of EGFR H773_V774insAH/BaF3
|
|
扫一扫，关注我们公众号
Copyright ©2021 www.cobioer.com All Rights Reserved. 南京科佰生物科技有限公司版权所有 苏ICP备13038923号