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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
NACC2-NTRK2/BaF3
| CBP73247 | |
| I. Introduction | |
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Cell Line Name： |
NACC2-NTRK2/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Freeze Medium: |
90% FBS+10% DMSO
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Complete Culture Medium: |
RPMI-1640+10%FBS+2ug/ml puromucin
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Mycoplasma Status: |
Negative |
| II.Background | |
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NACC2, NACC family member 2, is the nucleus accumbens-associated protein 2 that functions as a transcriptional repressor and regulates Tp53, through Mdm2, to decrease cell proliferation (PMID: 22926524). An NACC2 fusion with NTRK2 has been observed in pilocytic astrocytoma (PMID: 23817572). |
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| III. Representative Data | |
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1.NACC2-NTRK2/BaF3
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2. Anti-proliferation assay
Figure . Anti-proliferation assay of three reference compounds on the NACC2-NTRK2/BaF3 Stable Cell Line. |
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