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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
FGFR2-BICC1/BaF3
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CBP73268 |
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| I. Introduction | |
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Cell Line Name： |
FGFR2-BICC1/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Application: |
Anti-proliferation assay and PD assay |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| II.Background | |
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FGFR2-BICC1 results from the fusion of FGFR2 and BICC1, resulting in the ability to induce oligomerization, Fgfr kinase activity, Mapk signaling and transformation of cells in culture and in animal models (PMID: 23558953, PMID: 24122810, PMID: 28416604). FGFR2-BICC1 has been identified in intrahepatic cholangiocarcinoma (PMID: 25608663, PMID: 31899106). |
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| III. Representative Data | |
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1.WB of FGFR2-BICC1/BaF3
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2.Sanger of FGFR2-BICC1/BaF3
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3. Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 FGFR2-BICC1 Cells (C8). |
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