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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
AKT1 E17K/BaF3
| CBP73275 | |
| I. Introduction | |
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Cell Line Name： |
AKT1 E17K/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Freeze Medium: |
90% FBS+10% DMSO
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| II.Background | |
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AKT1 E17K lies within the PH domain of the Akt1 protein (UniProt.org). E17K leads to constitutive activation of Akt1, activates downstream signaling, and is transforming in culture (PMID: 17611497, PMID: 29533785, PMID: 27147599, PMID: 26701849). |
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| III. Representative Data | |
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1.WB of AKT1 E17K/BaF3
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2. Sanger of AKT1 E17K/BaF3
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3. Anti-proliferation assay |
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Figure 3. CTG Proliferation Assay of BaF3 AKT1 E17K Cells (C3) |
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