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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CYP2D6*2_p.S486T Reference Standard
| CBPA0001 | |
| Format | Genomic DNA |
| Description | CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients. |
| Technical Data | |
| Gene | CYP2D6 |
| AA Change | p.S486T |
| DNA Change | NM_000106.6_c.1457G>C |
| Chr position (GRCh38) | NC_000022.11_g.42126611C>G |
| Allelic Frequency | 100% |
| Zygosity | Homozygous |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4°C |
| Expiry | 36 months from the date of manufacture |
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