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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
FGFR2(E17)-AHCYL1(E2) Fusion
CBP20183R
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Format | RNA |
Description | FGFR2, fibroblast growth factor receptor 2, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR2 through activating mutations, fusions, and amplification increases cell proliferation and tumorigenesis (PMID: 22508544) and is observed in prostate (PMID: 30761180), breast, lung, uterine, and ovarian cancers (PMID: 29104507), while FGFR2 amplification (PMID: 31076567) and overexpression (PMID: 30662521) is commonly observed in gastric cancer. |
Technical Data | |
Left Gene | FGFR2 |
Left Breakpoint | chr10:123243212:- |
Right Gene | AHCYL1 |
Right Breakpoint | chr1:110551656:+ |
Cosmic ID | N/A |
Buffer | RNase-free H2O |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
RNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | -80℃ |
Expiry | 12 months from the date of manufacture |

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