科研细胞

科研细胞



药靶细胞

药靶细胞

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标准品



NGS靶向捕获探针

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产品编号

CBP74040

货号:

CBP74040

品牌:

Cobioer

规格:

T-25 Flask

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CBP74040
I. Background
Human CD137 (4-1BB; TNFRS9) is an inducible costimulatory molecule that activates T cells. CD137-CD137L mediated signaling has been shown to be important for proliferation, effector functions and survival of T cells. CD137 is also expressed in NK and NKT cells. Antibodies targeting CD137 activation in immune cells have demonstrated potent anti-tumor effects in cancer patients.

II. Description
Recombinant HEK293 cell constitutively expressing full length human CD137 (Genbank #NM_003811). Surface expression is confirmed by flow cytometry.

III. Introduction
Host Cell:	HEK293
Expressed gene:	CD137
Stability:	32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):	4-1BB, TNFRS9, Mitogen-Activated Protein Kinase 14, Signal Transducer And Activator Of Transcription 3, STAT3, MAPK14
Freeze Medium:	90% FBS+10% DMSO
Culture Medium:	DMEM+10%FBS+1ug/ml puromycin
Storage:	Liquid nitrogen
Application(s):	Binding Assay,FACS

IV. Description of Host Cell Line
Organism:	Homo sapiens, human
Tissue:	Embryonic kidney
Disease:	Normal
Morphology:	Epitheloid cell
Growth Properties:	Adherent

Ⅴ. Representative Data

Figure 1. Recombinant HEK293 cell constitutively expressing full length human CD137 (Genbank #NM_003811). Surface expression is confirmed by flow cytometry.