科研细胞

科研细胞

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药靶细胞

药靶细胞

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标准品

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NGS靶向捕获探针

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产品编号

CBP74105

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CBP74105

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Cobioer

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T-25 Flask

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CBP74105
I. Background
Antibody-dependent cell-mediated phagocytosis (ADCP) is one of the important mechanisms of action for antibody drug development.

II. Introduction
Host Cell:	Jurkat
Expressed gene:	FcγRIa_NFAT
Stability:	32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:	90% FBS+10% DMSO
Culture Medium:	RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin
Storage:	Liquid nitrogen
Application(s):	Functional(Report Gene) Assay

III. Description of Host Cell Line
Organism:	Human
Tissue:	Peripheral blood
Disease:	Childhood T acute lymphoblastic leukemia
Morphology:	Lymphoblast
Growth Properties:	Suspension

IV.Representative Data
Figure 1. Dose response of Rituximab in ADCP Bioassay Effector Cell FcyRⅠa/NFAT Reporter-Jurkat (C11)，the EC50 was 1.94ng/ml.