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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
ADCP Bioassay Effector Cell FcγRIa-NFAT/Jurkat
CBP74105 | |
I. Background | |
Antibody-dependent cell-mediated phagocytosis (ADCP) is one of the important mechanisms of action for antibody drug development. |
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II. Introduction | |
Host Cell: | Jurkat |
Expressed gene: | FcγRIa_NFAT |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
III. Description of Host Cell Line | |
Organism: | Human |
Tissue: | Peripheral blood |
Disease: | Childhood T acute lymphoblastic leukemia |
Morphology: | Lymphoblast |
Growth Properties: | Suspension |
IV.Representative Data | |
Figure 1. Dose response of Rituximab in ADCP Bioassay Effector Cell FcyRⅠa/NFAT Reporter-Jurkat (C11),the EC50 was 1.94ng/ml. |

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