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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
TP53 p.C176F Reference Standard
CBP10150
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Format | Genomic DNA |
Description | TP53 C176F lies within a zinc binding residue in the DNA-binding region of the Tp53 protein (UniProt.org). C176F is predicted to confer a loss of function to the Tp53 protein, as demonstrated by the inability to induce CDKN1A (p21) transcription in cell culture (PMID: 22090360). |
Technical Data | |
DNA Change: | c.527G>T |
AA Change | p.C176F |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 33.33% |
Transcript | ENST00000269305 |
Cosmic ID | COSM10645 |
Chr position(GRCh37) | chr17:7578403 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |

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