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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
TP53 p.R213Q Reference Standard
CBP10182
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Format | Genomic DNA |
Description | TP53 R213Q lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). R213Q results in a mild increase in cell proliferation in culture and increased tumor growth in animal models (PMID: 8080050), and therefore is predicted to confer a loss of function to the Tp53 protein. |
Technical Data | |
DNA Change | c.638G>A |
AA Change | p.R213Q |
Mutation type | Substitution - Nonsense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305 |
Cosmic ID | COSM10735 |
Chr position(GRCh37) | chr17:7578211 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | ![]() |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |

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