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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CTNNB1 p.S37A Reference Standard
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CBP10255
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| Format | Genomic DNA |
| Description | CTNNB1 S37A lies within the ubiquitination recognition motif of the Ctnnb1 protein and occurs at a Gsk3b phosphorylation site on the Ctnnb1 protein (PMID: 10347231). S37A confers a gain of function to the Ctnnb1 protein as demonstrated by decreased ubiquitination and stabilization of Ctnnb1-dependent transcription (PMID: 10347231). |
| Technical Data | |
| DNA Change | c.109T>G |
| AA Change | p.S37A |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000349496 |
| Cosmic ID | COSM5675 |
| Chr position(GRCh37) | chr3:41266112 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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