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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
KRAS p.G12C Reference Standard
CBP10294
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Format | Genomic DNA |
Description | KRAS G12C is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12C results in decreased Kras GTPase activity and activation of downstream signaling in cell culture and mouse models (PMID: 26037647 PMID: 16051643, PMID: 23455880). |
Technical Data | |
DNA Change | c.34G>T |
AA Change | p.G12C |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000311936 |
Cosmic ID | COSM516 |
Chr position(GRCh37) | chr12:25398285 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | ![]() |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |

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